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PythonsmolagentsLLM AgentsRetrievalTool UseMedical QA

Agentic and non-agentic multi-hop medical question answering

Compared an agentic evidence-search loop with controlled Wikipedia and Wikipedia + PubMed pipelines to study how tool use and retrieval strategy affect answer quality.

2025-08-14 · 1 min read

Overview

How do agentic and non-agentic multi-hop pipelines differ in medical QA accuracy, evidence use, and reliability?

System design

  • Built an agentic retrieval loop that searched for evidence and reviewed what it found
  • Let the model decide whether to continue gathering evidence or answer, with a 15-step execution cap
  • Built controlled Wikipedia and Wikipedia + PubMed comparison pipelines
  • Studied how iterative tool use and retrieval strategy changed answer quality

Results

  • Published the results at BioCreative IX / IJCAI 2025
  • Produced a side-by-side analysis of agentic and non-agentic multi-hop system behavior